Structural Biology

22 results.

March 20, 2022 Cryo-EM reveals how ‘911’ molecule helps fix damaged DNA

GRAND RAPIDS, Mich. (March 21, 2022) — When something goes wrong during DNA replication, cells call their own version of 911 to pause the process…

March 23, 2021 Today is World Tuberculosis Day. Here’s what you need to know.

On March 24, 1882, German physician Dr. Robert Koch announced that he had identified the bacterium that causes tuberculosis (TB), a deadly disease that at…

June 2, 2020 Atomic blueprint of ‘molecular machine’ reveals role in membrane protein installation

GRAND RAPIDS, Mich. (June 3, 2020) — Van Andel Institute scientists have revealed the first known atomic structure of a “molecular machine” responsible for installing…

January 30, 2020 10 research trends we’re excited to watch in the next decade

With a new decade comes a new world of possibility and innovation waiting to be unleashed in labs at Van Andel Institute and across the…

October 2, 2018 High-resolution “blueprint” reveals mechanism that helps E. coli infect the urinary tract

GRAND RAPIDS, Michigan (October 3, 2018) — A common gut bacterium uses a unique assembly apparatus to build hair-like structures that help it infect the…

May 9, 2018 Microbes from marine volcanic vents reveal how humans adjusted to a changing atmosphere

GRAND RAPIDS, Mich., and ATHENS, Ga. (May 10, 2018) — Ancient microbes that thrive in some of the world’s most extreme environments and modern-day humans…

April 24, 2018 Meet the scientist behind the science: Dr. Huilin Li

There is an old adage in science — structure informs function, meaning the shapes of individual molecules are closely linked to their jobs in the…

January 21, 2018 Cryo-EM reveals critical protein-modifying complex and potential drug target

GRAND RAPIDS, Mich. (Jan. 22, 2018)—Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, possibly paving the way for the…