Cryo-EM

11 results.

March 24, 2024 Tuberculosis is an ancient problem. Modern technology is helping solve it

Van Andel Institute’s Dr. Huilin Li is using modern technology to solve an ancient problem that still has devastating consequences today: tuberculosis (TB), a…

January 18, 2024 Structural study points the way to better malaria drugs

Structural insights into a potent antimalarial drug candidate’s interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies,…

March 21, 2022 Cryo-EM reveals how ‘911’ molecule helps fix damaged DNA

GRAND RAPIDS, Mich. (March 21, 2022) — When something goes wrong during DNA replication, cells call their own version of 911 to pause the process…

June 3, 2020 Atomic blueprint of ‘molecular machine’ reveals role in membrane protein installation

GRAND RAPIDS, Mich. (June 3, 2020) — Van Andel Institute scientists have revealed the first known atomic structure of a “molecular machine” responsible for installing…

October 3, 2018 High-resolution “blueprint” reveals mechanism that helps E. coli infect the urinary tract

GRAND RAPIDS, Michigan (October 3, 2018) — A common gut bacterium uses a unique assembly apparatus to build hair-like structures that help it infect the…

April 25, 2018 Meet the scientist behind the science: Dr. Huilin Li

There is an old adage in science — structure informs function, meaning the shapes of individual molecules are closely linked to their jobs in the…

January 22, 2018 Cryo-EM reveals critical protein-modifying complex and potential drug target

GRAND RAPIDS, Mich. (Jan. 22, 2018)—Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, possibly paving the way for the…

October 23, 2017 Cryo-EM reveals ignition mechanism for DNA replication

GRAND RAPIDS, Mich. (Oct. 23, 2017) — An international team of scientists, led by scientists at Van Andel Research Institute, Cold Spring Harbor Laboratory and…